Hello Friends

I am Sakshi Garg,  I would like to share my notes with you which I have prepared for preparation. These might be useful for you.

I would also like to know your views regarding each topic, any queries regarding the notes and also if you would like to share any information with me I will be highly thankful.I will be writing breifly and in a very simple language.

Today, the topic that I am going to discuss is Tranduction.



Transduction is transfer of bacterial genes by virus.

Transduction are of two types:
 1. Generalized Transduction
2.Specialized Transduction


Generalized Transduction:

This occurs during lytic cycle of virulent and temperate phage and can transfer any part of bacterial genome.

During packaging of capsids in lytic phase random fragments of bacterial DNA can also be packed by mistake in some capsids.

Since viral capsid can contain limited amount of DNA, the viral DNA is left behind. These virus can inject DNA of bacteria into other bacteria after infection but does not initiate lytic cycle.

Double stranded DNA remain Double stranded during transfer and integrates into host bacterium or endogenote.

Specialized Transduction:

also known as restricted Transduction.

When prophage leaves the bacterial genome the cleavage or excision of viral DNA is improper.

Phage may contain portion of bacterial DNA next to integration sites.

This type of transducing phage is defective and cannot reproduce without assistance.

This can be explained with this example: phage att site or attachment site and bacterial att site are similar and can recombine with each other.
Since viral att site are next to bacterial gal and bio sites these can be carried by lambda phage due to mistake in excising.

Stable transduction may arise through recombination of bacterial genome nad phage chromosome.

Hope this will help you all. See you all in next blog.
Thnkyou for reading.